Our Pipeline

Genetix leverages our expertise in genetic medicine to bring transformative treatments to patients in need

Our clinical trials and research are designed to expand treatment options and address areas of high unmet need.
Product Indication Research Clinical development Approved

LYFGENIA™
(lovotibeglogene autotemcel)

Sickle Cell Disease

Sickle cell disease patients 12 years and older with a history of vaso-occlusive events
 
Sickle cell disease patients under the age of 12
 

Ongoing Study:
HGB-210

ZYNTEGLO™
(begibeglogene autotemcel)

Transfusion-dependent
Beta-thalassemia

Adult and pediatric patients with transfusion dependent beta-thalassemia
 

SKYSONA™
(elivaldogene autotemcel)

Cerebral Adrenoleukodystrophy

Pediatric boys with early, active CALD without an available HLA-matched donor for allogenic HSCT*
 

CALD = cerebral adrenoleukodystrophy
*Human leukocyte antigen-matched donor for allogenic hematopoietic stem cell transplantation.

Product

LYFGENIA™
(lovotibeglogene autotemcel)

Sickle Cell Disease


Indication

Sickle cell disease patients 12 years and older with a history of vaso-occlusive events


ResearchClinical developmentApproved
 

Indication

Sickle cell disease patients under the age of 12


ResearchClinical developmentApproved
 

Ongoing Study: HGB-210

Product

ZYNTEGLO™
(begibeglogene autotemcel)

Transfusion-dependent
Beta-thalassemia


Indication

Adult and pediatric patients with transfusion dependent beta-thalassemia


ResearchClinical developmentApproved
 

Product

SKYSONA™
(elivaldogene autotemcel)

Cerebral Adrenoleukodystrophy


Indication

Pediatric boys with early, active CALD without an available HLA-matched donor for allogenic HSCT*


ResearchClinical developmentApproved
 

CALD = cerebral adrenoleukodystrophy
*Human leukocyte antigen-matched donor for allogenic hematopoietic stem cell transplantation.

Continue Exploring

Genetic Medicine

Learn how our approach is designed to address disease at its source

Patient Experience

Understand what to expect at each step of the treatment journey